Date rape is funny? Do you mean that scene in which Lucy shot tranquilizers at Gru's date? Because it was very clear that was done to prevent her from embarrassing Gru by ripping off his wig. I don't think the vibe of the scene was "it's okay to drug women to get what you want from them".
I also don't think Gru's objections to his potential dates was that they were ugly. One was clumsy (knocking over tables at Agnes' party) and the other one was rude and shallow.
My problem with this film is how Lucy Wilde seemed to get dumber as the movie went on. First she captured Gru in an awesome way and...that's all she did?
Then again, this is the movie that thinks date rape is funny, that Gru can't date someone who isn't physically perfect, and marriage is the happiest ending for the female protagonist.